Is my PSA (Prostate-Specific Antigen) normal?
Free blood test checker · Standard + longevity-optimal ranges
What is a normal PSA level?
PSA is a protein produced by both normal and malignant prostate cells. Normal is below 4.0 ng/mL, though many urologists now use age-adjusted ranges. Elevated PSA can indicate prostate cancer, benign prostatic hyperplasia (BPH), or prostatitis — PSA is not cancer-specific. The AUA recommends shared decision-making for screening starting at age 55.
| Range | Values |
|---|---|
| Standard Reference | 0–4 ng/mL |
| High Risk | > 10 ng/mL |
What causes abnormal PSA levels?
Elevated PSA is caused by prostate cancer (most concerning), benign prostatic hyperplasia (BPH — the most common cause), prostatitis (infection or inflammation), urinary tract infection, recent ejaculation (within 24-48 hours), vigorous cycling, and prostate manipulation (digital rectal exam, catheterization). Certain medications like 5-alpha reductase inhibitors (finasteride, dutasteride) artificially lower PSA by ~50%.
When should you see a doctor?
See your doctor if PSA is above 4.0 ng/mL, if PSA velocity exceeds 0.75 ng/mL per year, or if you have urinary symptoms (frequency, urgency, weak stream, nocturia). PSA above 10 ng/mL warrants urgent referral. Also consult if you are over 50 and have never been screened.
PSA and longevity
Prostate cancer is the most common non-skin cancer in men, but the vast majority of cases are slow-growing and unlikely to be fatal. The challenge with PSA screening is overdiagnosis — detecting cancers that would never cause symptoms. Modern risk stratification uses PSA density (PSA divided by prostate volume), free-to-total PSA ratio, and MRI-guided biopsy to reduce unnecessary interventions. For longevity-focused men, establishing a baseline PSA at age 40-45 is valuable — a PSA below 1.0 ng/mL at age 40-45 is associated with very low lifetime risk of aggressive prostate cancer.
Where to get a PSA test
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Related biomarkers
These biomarkers are often tested alongside PSA for a more complete picture.
Frequently asked questions
What is a normal PSA level?
Does high PSA always mean cancer?
How often should I check PSA?
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Sources: Reference ranges based on AHA/ACC, ADA, and AACE clinical guidelines. Biological variation data from Ricos/Westgard database. Longevity-optimal ranges reflect targets used by preventive and functional medicine practitioners.
Last reviewed: April 2026. This tool provides general health information and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider about your specific results.