Is my Uric Acid normal?
Free blood test checker · Standard + longevity-optimal ranges
What is a normal Uric Acid level?
Uric acid is a waste product from purine metabolism. Elevated levels (hyperuricemia) can cause gout — painful joint inflammation — and kidney stones. Normal is 2.5-7.0 mg/dL, but longevity physicians target below 5.0 mg/dL. Over 9 million Americans have gout, and prevalence is rising.
| Range | Values |
|---|---|
| Standard Reference | 2.5–7 mg/dL |
| Optimal | 2.5–5 mg/dL |
| Longevity Optimal | < 5.0 mg/dL |
| High Risk | > 9 mg/dL |
What causes abnormal Uric Acid levels?
High uric acid is caused by overproduction (high-purine diet, cell turnover from cancer treatment) or underexcretion (kidney disease, dehydration, alcohol, medications like diuretics and low-dose aspirin). Fructose is uniquely problematic — it's the only sugar that directly increases uric acid production. Obesity and metabolic syndrome are strongly associated.
When should you see a doctor?
See your doctor if uric acid is above 7.0 mg/dL, if you have a history of gout attacks (sudden, severe joint pain), kidney stones, or if levels are rising over time. Also consult if you have metabolic syndrome, as uric acid may be contributing to insulin resistance and cardiovascular risk.
Uric Acid and longevity
Uric acid is emerging as more than just a gout marker — it is increasingly recognized as an independent cardiovascular risk factor and a driver of metabolic dysfunction. Elevated uric acid impairs endothelial function, promotes oxidative stress, and activates inflammatory pathways. Fructose is uniquely problematic because it is the only sugar that directly increases uric acid production via purine degradation. Dr. Rick Johnson's research has shown that uric acid may directly contribute to insulin resistance, hypertension, and fatty liver disease through mitochondrial oxidative stress. The longevity target of below 5.0 mg/dL reflects the threshold below which these metabolic effects are minimized. Interestingly, uric acid also functions as an antioxidant at normal levels — it is the U-shaped relationship that makes the optimal range narrow.
Where to get a Uric Acid test
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Related biomarkers
These biomarkers are often tested alongside Uric Acid for a more complete picture.
Frequently asked questions
What is a normal uric acid level?
What foods raise uric acid?
Can high uric acid exist without gout?
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Sources: Reference ranges based on AHA/ACC, ADA, and AACE clinical guidelines. Biological variation data from Ricos/Westgard database. Longevity-optimal ranges reflect targets used by preventive and functional medicine practitioners.
Last reviewed: April 2026. This tool provides general health information and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider about your specific results.