Is my Progesterone normal?
Free blood test checker · Standard + longevity-optimal ranges
What is a normal Progesterone level?
Progesterone is primarily produced by the ovarian corpus luteum after ovulation and by the placenta during pregnancy. Normal range varies dramatically with menstrual phase: 0.1-0.9 ng/mL (follicular), 1.8-24 ng/mL (luteal), and up to 290 ng/mL in pregnancy. In men, normal range is 0.1-0.2 ng/mL. Progesterone confirms ovulation and supports early pregnancy.
| Range | Values |
|---|---|
| Standard Reference | 0.1–25 ng/mL |
What causes abnormal Progesterone levels?
Low progesterone is caused by anovulatory cycles (PCOS is the most common cause), luteal phase deficiency, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia, and perimenopause. Elevated progesterone outside of pregnancy can indicate congenital adrenal hyperplasia (21-hydroxylase deficiency) or ovarian tumors. Stress and extreme exercise suppress the HPG axis and reduce progesterone production.
When should you see a doctor?
See your doctor if mid-luteal progesterone is below 3 ng/mL (suggests anovulation), if you are experiencing irregular periods, difficulty conceiving, or recurrent early pregnancy loss. Low progesterone in early pregnancy (below 10 ng/mL) may indicate ectopic pregnancy or impending miscarriage.
Progesterone and longevity
Progesterone is primarily discussed in the context of reproductive health, but it also has significant neurological and metabolic effects. Progesterone is neuroprotective — its metabolite allopregnanolone modulates GABA receptors and has anxiolytic and sleep-promoting effects. The precipitous drop in progesterone during perimenopause contributes to sleep disruption, anxiety, and mood changes. Bioidentical progesterone replacement is increasingly used in hormone replacement therapy, with evidence suggesting it has a better cardiovascular safety profile than synthetic progestins.
Where to get a Progesterone test
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Related biomarkers
These biomarkers are often tested alongside Progesterone for a more complete picture.
Frequently asked questions
What is a normal progesterone level?
How does progesterone confirm ovulation?
What causes low progesterone?
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Sources: Reference ranges based on AHA/ACC, ADA, and AACE clinical guidelines. Biological variation data from Ricos/Westgard database. Longevity-optimal ranges reflect targets used by preventive and functional medicine practitioners.
Last reviewed: April 2026. This tool provides general health information and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider about your specific results.